המעבדה לכימיה אורגנית ואי-אורגנית

 

Divergent Reactivity of PolyBorylated Compounds
Ahmad Masarwa
Institute of Chemistry, The Hebrew University of Jerusalem
Ahmad.Masarwa1@mail.huji.ac.il
Abstract: Polyborylated derivatives (I), including the gem-diboryl species, are known as an emerging class with good potential for novel synthetic applications.1-2 The special properties and structures of polynucleophile polyboryl compounds
(termed organo-polymetallics) have attracted increasing attention from synthetic chemists, particularly in constructing C–C/ C–heteroatom bonds.1-2 In recent years, our research group has adopted the polyborylalkene species as coupling partners in synthetic chemistry through novel transformations (Figure 1). Moreover, we have demonstrated that our methods can serve as an endpoint late-stage diversification and as a site for subsequent functionalization of simple organic molecules, natural compounds, and bioactive molecules (Figure 1).3-5 In my seminar, I will address our efforts toward the divergent reactivity of gem-diborylakenes for synthetic diversity, these include radical-mediated transformations, cycloaddition reactions, and polymerization.3-6