David Ginsburg Memorial Colloquium: Physical Organic Principles in Selective Reaction Design
Hall No. 1
Professor Ryan Gilmour, Institute for Organic Chemistry, Westfälische Wilhelms-Universität Münster, Münster, Germany
Physical Organic Principles in Selective Reaction Design
One of the greatest challenges facing organic chemistry is the synthesis of function, and so a central theme in the Gilmour Laboratory is molecular design. The ability to construct predictably functional molecules requires the conception of systems with defined properties. As such any process must logically commence with a process of molecular design. Research in our laboratory is broadly based on leveraging physical organic principles to design novel materials with predictable conformational behaviour and/or reactivities in 2D and 3D space. In this lecture, advances in contra-thermodynamic E → Z isomerization of alkenes via energy transfer catalysis will be discussed together with our latest contributions to main group catalysis-enabled selective fluorination and glycochemistry.